The group’s activity is organised into four axes that reflect a complete research pathway—from synthesis and biofunctionalisation to validation and transfer.
Research Highlights
Translating nanotechnology from concept to clinic
The group’s activity is organised into four axes that reflect a complete research pathway—from synthesis and biofunctionalisation to validation and transfer.
Axis A
Nanoconjugates & therapeutic delivery
Multifunctional nanoconjugates based on natural and synthetic polymers engineered to transport antibiotics, siRNA, antimicrobial peptides or inorganic nanoparticles. These systems target infections such as tuberculosis, as well as pancreatic and colon cancer and specific rare diseases.
Magnetic nanoparticles capable of generating heat under external fields to modulate enzymes, receptors and cellular pathways. These systems support controlled release, mechanobiological studies and remote actuation strategies relevant to oncology and biosensing.
Lateral-flow and calorimetric biosensing platforms that use plasmonic nanoparticles to achieve femtomolar sensitivity. Applications include liquid biopsy approaches for early pancreatic cancer detection and point-of-care diagnostics for respiratory viruses such as SARS-CoV-2, influenza and RSV.
Protocols aligned with GLP/GMP principles and shared processes that connect INMA infrastructures, materials characterisation, biological testing and regulatory knowledge. These frameworks support the safe, efficient and reproducible transfer of nanoformulations and medical nanodevices.