Lucía Gutiérrez Lab

Iron-based nanoparticle characterization, biodistribution tracking, and magnetic hyperthermia methodologies.

Portrait of Lucía Gutiérrez Marruedo

Lab summary

Lucía Gutiérrez focuses on iron-based magnetic nanoparticles, integrating advanced physical characterization with biomedical applications.

Her group develops methodologies to correlate structure with functional properties, including accurate specific loss power (SLP) determinations for heating efficiency and regulatory assessment.

She deploys magnetic characterization to track nanoparticle biodistribution/degradation in complex biological environments while exploring magnetic hyperthermia plus magneto-mechanical stimulation for cancer therapies and extracellular matrix modulation.

Lab quick facts

  • ORCID: 0000-0003-2366-3598
  • Focus: AC magnetic susceptibility, SLP benchmarking, magnetic hyperthermia
  • Application areas: Oncology, iron supplement regulation, extracellular matrix modulation

Research lines

  1. Advanced characterization of iron-based nanoparticles Developing methodologies for SLP determination to connect nanoparticle structure with biomedical performance and support regulatory assessments.
  2. Magnetic characterization for biodistribution tracking Using AC magnetic susceptibility to monitor nanoparticle fate, transformations, and heating loss inside biological environments.
  3. Magnetic hyperthermia therapies Employing iron-oxide and mixed-ferrite nanoparticles to deliver localized heating in vitro/in vivo and explore extracellular matrix modulation strategies.
  4. Intracellular magneto-mechanics Studying mechanical forces generated when nanoparticle-loaded vesicles encounter alternating magnetic fields.

Team

  • Maura Rabade
  • Lucía Gutiérrez Marruedo
  • Amira Páez
  • Nansi Ciiciumaru
  • Ariana García

Latest publications

See all publications on ORCID

Instrumentation & methods

  • AC magnetic susceptibility (AC-Sus) pipelines
  • SLP benchmarking + SLPCalculator.com dataset contributions
  • Magnetic hyperthermia testbeds (in vitro / in vivo)
  • Magneto-mechanical stimulation rigs for vesicle-loaded cells